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Title: IGF-1 modulates gene expression of proteins involved in inflammation, cytoskeleton, and liver architectureLanguage: InglésRepository: 34Subject: acute phase protein / autacoid / lipid / messenger RNA / scleroprotein / somatomedin C / cadherin / cytoskeleton protein / insulin-like growth factor-1, mouse / somatomedin receptor / tight junction protein / acute phase response / animal experiment / animal tissue / Article / cell junction / cell polarity / controlled study / cytoskeleton / extracellular matrix / gene expression regulation / gene overexpression / heterozygosity / histology / igf1 gene / inflammation / lipid peroxidation / liver structure / liver tissue / male / microarray analysis / mouse / murine model / nonhuman / oxidative stress / protein analysis / protein blood level / protein deficiency / protein function / reverse transcription polymerase chain reaction / wild type / animal / comparative study / cross breeding / desmosome / gene expression profiling / genetics / hepatitis / immunology / liver / metabolism / pathology / subcutaneous drug administration / transgenic mouse / Acute-Phase Proteins / Animals / Cadherins / Crosses, Genetic / Cytoskeletal Proteins / Desmosomes / Extracellular Matrix Proteins / Gene Expression Profiling / Gene Expression Regulation / Hepatitis / Inflammation Mediators / Injections, Subcutaneous / Insulin-Like Growth Factor I / Lipid Peroxidation / Liver / Male / Mice / Mice, Transgenic / Oxidative Stress / Receptors, Somatomedin / Tight Junction Proteins / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Partial IGF-1 deficiency is sufficient to reduce heart contractibility, angiotensin II sensibility, and alter gene expression of structural and functional cardiac proteinsLanguage: InglésRepository: 34Subject: angiotensin II / calcium / connective tissue growth factor / contractile protein / protein Grem1 / scleroprotein / somatomedin B / somatomedin B receptor / somatomedin binding protein 1 / somatomedin binding protein 2 / somatomedin binding protein 3 / somatomedin binding protein 4 / somatomedin binding protein 5 / somatomedin binding protein 6 / somatomedin C / somatomedin C receptor / unclassified drug / bradykinin / animal experiment / animal model / animal tissue / Article / calcium homeostasis / controlled study / coronary artery blood flow / Ctgf gene / extracellular matrix / gene / gene expression / Grem1 gene / heart muscle contractility / heart muscle fibrosis / heart weight / histology / Igf1 gene / Igf1r gene / Igf2 gene / Igf2r gene / Igfbp1 gene / Igfbp2 gene / Igfbp3 gene / Igfbp4 gene / Igfbp5 gene / Igfbp6 gene / male / mouse / nonhuman / protein blood level / real time polymerase chain reaction / regulatory mechanism / reperfusion injury / animal / body weight / cardiac muscle / deficiency / drug effects / gene expression regulation / genetics / heart contraction / hemodynamics / metabolism / organ size / pathology / perfusion / transgenic mouse / vasoconstriction / vasodilatation / Angiotensin II / Animals / Body Weight / Bradykinin / Extracellular Matrix / Gene Expression Regulation / Hemodynamics / Insulin-Like Growth Factor I / Mice, Transgenic / Myocardial Contraction / Myocardium / Organ Size / Perfusion / Real-Time Polymerase Chain Reaction / Vasoconstriction / Vasodilation / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Antitumor macrophage response to bacillus pumilus ribonuclease (Binase)Language: InglésRepository: 34Subject: Bacillus pumilus ribonuclease / bacterial enzyme / interleukin 10 / interleukin 4 / interleukin 6 / monocyte chemotactic protein 1 / myeloid differentiation factor 88 / ribonuclease / toll like receptor / toll like receptor adaptor molecule 1 / transcription factor RelA / tumor necrosis factor / unclassified drug / animal cell / Article / Bacillus pumilus / controlled study / cytokine release / human / human cell / immune response / macrophage / malignant neoplasm / mouse / nonhuman / polarization / protein expression / RAW 264.7 cell line / THP-1 cell line / 7 INGENIERÍA Y TECNOLOGÍA
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Title: A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray databaseLanguage: InglésRepository: 34Subject: 1 naphthyl isothiocyanate / acetylsalicylic acid / allopurinol / allyl alcohol / amiodarone / azathioprine / benzbromarone / bromobenzene / carbamazepine / carbon tetrachloride / chlorpromazine / cimetidine / clofibrate / coumarin / cyclophosphamide / cytochrome P450 family 1 / diazepam / diclofenac / doxepin / ethionine / fluphenazine / flutamide / gemfibrozil / glibenclamide / griseofulvin / haloperidol / hexachlorobenzene / indometacin / paracetamol / unindexed drug / cytotoxin / algorithm / Article / cluster analysis / data base / gene expression / genomics / human / liver cell / liver toxicity / machine learning / microarray analysis / nonhuman / skin absorption / toxic hepatitis / xenobiotic metabolism / animal / DNA microarray / dose response / drug effects / genetic database / genetics / liver / metabolism / mouse / preclinical study / procedures / time factor / toxicogenetics / unsupervised machine learning / Animals / Chemical and Drug Induced Liver Injury / Cytotoxins / Databases, Genetic / Dose-Response Relationship, Drug / Drug Evaluation, Preclinical / Genomics / Humans / Liver / Mice / Oligonucleotide Array Sequence Analysis / Time Factors / Toxicogenetics / Unsupervised Machine Learning / 7 INGENIERÍA Y TECNOLOGÍA
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Title: The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob miceLanguage: InglésRepository: 34Subject: eprotirome / hormone receptor stimulating agent / liothyronine / sobetirome / thyroid hormone receptor / thyroid hormone receptor agonist / triacylglycerol / unclassified drug / 3-((3,5-dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid / acetic acid derivative / anilide / glucose 6 phosphatase / glucose blood level / phenol derivative / animal experiment / animal model / animal tissue / Article / body temperature / controlled study / glucose tolerance / glycemic control / insulin resistance / insulin sensitivity / liver level / male / mouse / nonalcoholic fatty liver / nonhuman / ob/ob mouse / agonists / animal / biosynthesis / dose response / drug effects / enzyme induction / metabolism / mouse mutant / Non-alcoholic Fatty Liver Disease / time factor / Mus / Acetates / Anilides / Animals / Blood Glucose / Body Temperature / Dose-Response Relationship, Drug / Enzyme Induction / Glucose-6-Phosphatase / Insulin Resistance / Male / Mice / Mice, Obese / Phenols / Receptors, Thyroid Hormone / Time Factors / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Proinflammatory cytokines are soluble mediators linked with ventricular arrhythmias and contractile dysfunction in a rat model of metabolic syndromeLanguage: InglésRepository: 34Subject: Blood pressure / Body fluids / Calcium / Gene expression / Heart / Metabolism / Potable water / Rats / Cardiovascular risk / Chronic inflammation / Contractile dysfunction / Mechanical performance / Metabolic syndromes / Pro-inflammatory cytokines / Ventricular arrhythmias / Ventricular fibrillation / Calcium compounds / calcium / complementary DNA / cytokine / cytokine receptor / interleukin 10 / interleukin 1beta / interleukin 6 / isoprenaline / leptin / leptin receptor / messenger RNA / triacylglycerol / tumor necrosis factor / tumor necrosis factor receptor associated factor 1 / tumor necrosis factor receptor associated factor 2 / animal cell / animal experiment / animal model / animal tissue / Article / beta adrenergic stimulation / blood pressure / body weight / cardiac muscle cell / comparative study / controlled study / ex vivo study / gene expression / heart function / heart muscle contractility / heart tissue / heart ventricle arrhythmia / heart ventricle extrasystole / immunopathogenesis / inflammation / intra-abdominal fat / isolated heart / male / metabolic syndrome X / nonhuman / rat / sugar intake / triacylglycerol blood level / Animals / Diagnosis / Diseases / Medicine / 7 INGENIERÍA Y TECNOLOGÍA
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Title: The 482Ser of PPARGC1A and 12Pro of PPARG2 Alleles Are Associated with Reduction of Metabolic Risk Factors even Obesity in a Mexican-Mestizo PopulationLanguage: InglésRepository: 34Subject: adipocytokine / apolipoprotein A1 / apolipoprotein B / glucose / high density lipoprotein cholesterol / insulin / leptin / low density lipoprotein cholesterol / peroxisome proliferator activated receptor gamma 2 / peroxisome proliferator activated receptor gamma coactivator 1alpha / resistin / triacylglycerol / very low density lipoprotein cholesterol / genetic marker / peroxisome proliferator activated receptor gamma / PPARGC1A protein, human / transcription factor / abdominal obesity / adipogenesis / adult / allele / Article / body fat / body mass / controlled study / dyslipidemia / female / genetic polymorphism / genetic risk / glucose metabolism / hip circumference / human / major clinical study / male / Mestizo / Mexican / obesity / phenotype / polymerase chain reaction / restriction fragment length polymorphism / waist circumference / age distribution / aged / ethnology / genetic association study / genetic predisposition / genetics / incidence / Metabolic Diseases / Mexico / middle aged / risk factor / sex ratio / single nucleotide polymorphism / very elderly / young adult / Adult / Age Distribution / Aged / Aged, 80 and over / Alleles / Female / Genetic Association Studies / Genetic Markers / Genetic Predisposition to Disease / Humans / Incidence / Male / Middle Aged / Obesity / Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha / Polymorphism, Single Nucleotide / PPAR gamma / Risk Factors / Sex Distribution / Transcription Factors / Young Adult / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Liver fibrosis and mechanisms of the protective action of medicinal plants targeting inflammation and the immune responseLanguage: InglésRepository: 34Subject: andrographolide / antifibrotic agent / antiinflammatory agent / baicalin / berberine / caffeine / chemokine / chlorogenic acid / curcumin / cytokine / Emblica officinalis extract / Ginkgo biloba extract / ginsenoside Rd / ginsenoside Rg 1 / ginsenoside Rg 3 / glycyrrhizic acid / herbaceous agent / immunoglobulin enhancer binding protein / kutkin / nicotinic acid / Phyllanthus amarus extract / Phyllanthus rheedi extract / Phyllanthus urinaria koreanis extract / plant extract / pyrazinoic acid / salvianolic acid A / silymarin / sodium tanshinone IIA / tanshinone IIA / unclassified drug / unindexed drug / Andrographis paniculata / antiinflammatory activity / Article / Berberis aristata / Bupleurum / Bupleurum falcatum / CD4+ T lymphocyte / CD8+ T lymphocyte / coffee / Curcuma longa / drug mechanism / drug targeting / Ginkgo biloba / ginseng / Glycyrrhiza glabra / human / immune response / inflammation / liver fibrosis / liver protection / macrophage / mast cell / medicinal plant / natural killer cell / neutrophil / nonhuman / pathogenesis / Phyllanthus / Picrorhiza kurroa / priority journal / Salvia miltiorrhiza / Scutellaria baicalensis / Silybum marianum / stellate cell / thrombocyte / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Enrichment of the cancer stem phenotype in sphere cultures of prostate cancer cell lines occurs through activation of developmental pathways mediated by the transcriptional regulator ΔNp63αLanguage: InglésRepository: 34Subject: Bcl2 related protein A1 / CD133 antigen / delta NP63alpha protein / early growth response factor 1 / regulator protein / unclassified drug / glycoprotein / leukocyte antigen / peptide / PROM1 protein, human / tumor marker / Article / BCL2A1 gene / bioassay / cancer stem cell / CD133+ cancer stem cell / cell growth / clonogenesis / controlled study / drug resistance / EGR1 gene / flow cytometry / GAS1 gene / gene expression profiling / human / human cell / IGFBP3 gene / in vitro study / in vivo study / male / phenotype / prostasphere assay / prostate cancer cell line / protein expression / protein function / transcription regulation / tumor invasion / upregulation / gene expression regulation / metabolism / pathology / prostate tumor / tumor cell line / AC133 Antigen / Antigens, CD / Biomarkers, Tumor / Cell Line, Tumor / Gene Expression Profiling / Gene Expression Regulation, Neoplastic / Glycoproteins / Humans / Male / Neoplastic Stem Cells / Peptides / Phenotype / Prostatic Neoplasms / 7 INGENIERÍA Y TECNOLOGÍA
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